Get Prepared for ENDOSURE Test
ENDOSURE is the Only Tier 1 Diagnostic Test for Endometriosis
Testing Is Simple.
WHEN to Book Your ENDOSURE Test
Guidelines:
- We can’t test when you are menstruating. If you start your period, call your clinic right away to rebook
- Talk to a healthcare professional about when to book your ENDOSURE test.
Arrive Prepared for ENDOSURE Testing
DO:
- Take prescribed medication with sips of water, at least 2 hours before your test.
- Wear looser separates (ex. shirt and pants or skirt).
- Refrain for using lotions, oils, self-tanning products or perfumes on test day.
- Put your phone on airplane mode and remove any wearables and blue-toothed devices. Put them away for the duration of the test.
DON’T:
- Don’t eat or drink anything for 8 hours before testing. No fluids are allowed, including water. Avoid gum gum or lozenges. Ensure there is no caffeine from any source.
- 48 hours / 2 days before your test don’t use opioid pain medications that slow the bowel
- 72 hours / 3 days before your test don’t use anti-spasmodic, prokinetics, bowel stimulants or gastric motility agents which change intestinal movement.
- 30 days before your test discontinue use of THC containing cannabis products and GLP-1 receptor agonists that slow stomach emptying.
- Do not stop medications until speaking with your doctor or your pharmacist. If in doubt, print the Patient Information brochure and consult with your doctor or pharmacist in advance of testing.
What to Expect
- Testing takes about an hour, so use the restroom before you start.
- Clothes stay on during the test, but wear looser separates.
- You lay back on an examination table or reclining chair and relax. Get comfortable.
- Three sensors are placed on your abdomen, a respiratory belt is positioned to monitor your breathing.
- The tester collects information from you and coaches you on patient behaviour – no talking, staying still during testing and breathing normally.
The tester runs an equipment test, and then a 10-minute baseline. You drink water. This incites GIMA activity. The EVG machine records this GIMA activity for 30-minutes which are used for diagnostic results.
Your ENDOSURE test provider will give you instructions on receiving your test results.
Frequently Asked Questions
What should I expect during an ENDOSURE test?
Testing is painless and takes just under an hour. You will be asked to relax, avoid movement, avoid talking, and to breathe normally. ENDOSURE test is most similar to an ECG, but for the gut: electrodes record gastrointestinal myoelectric activity (GIMA) for 30 minutes. Be sure to use the bathroom first, you cannot move once testing begins.
How long does an ENDOSURE test take?
Testing takes just under an hour. Arrive 15 minutes before your testing time to fill in a questionnaire, then plan to be in testing for an hour: 20 minutes preparation + 30-minutes active GIMA recording.
Are there any risks associated with ENDOSURE?
There are no risks associated with this test. There are no components that are used during the test equipment that are harmful. No anesthesia is required for this test.
When should I schedule my ENDOSURE test?
Scheduling ENDOSURE Test:
- Testing cannot be done during menstruation.
- Ensure other diseases you may have are stable. List of concening illnesses:
-Celiac disease
-Crohn’s or Ulcerative Colitis
-Small bowel bacterial overgrowth
-Bowel obstruction
-Viral or Bacterial gastroenteritis
-Persistent Nausea and vomiting - Wait 2 WEEKS after resolution of:
-Acute gastrointestinal illness
-Intra-abdominal infection
-Intra-pelvic infection
- Wait 3 MONTHS after recovery from abdominal or pelvic surgery of any type
How can I arrive for ENDOSURE testing prepared?
Preparation includes:
Up to 2-hours before test:
Take prescribed medications with small sips of water at least 2-hours before the test.
8-hours before test:
No food, water, fluids, gum
No caffeine (coffee, tea, energy drinks)
2-Days/48 hours before test
No opioid pain medications that slow the bowel:
Codeine, Oxycodone, Hydrocodone +/- acetaminophen, Morphine, hydromorphone, Tramadol +/- acetaminophen
3-Days/72 hours before test
Medications that change intestinal movement:
Metoclopramide, Domperidone, Itopride, Levosulpiride, Erythromycin, Dicyclomine, Hyoscine butylbromide, Loperamide
30-days before test
Discontinue THC containing cannabis products
GLP-1 receptor agonists that slow stomach emptying: Tirzepatide – Mounjaro, Semaglutide – Ozempic/Wegovy
Do not stop medications until speaking with your doctor or your pharmacist. If in doubt, please check with your doctor or pharmacist in advance of the test.
What should I do to arrive prepared on the day of the test?
- Plan to be in testing for an hour; 20 minutes prep + 30-minutes active recording.
- Loose-fitting, 2-piece clothing that is relaxed and warm should be worn.
- Do not use lotions, oils, self-tanning products or perfumes.
- Use the bathroom first, you cannot move once testing begins.
- Smartphones, watches and other electronic devices should be shut off and put away.
What if I'm diabetic?
A 200 kcal meal is allowed 2 hours or more before testing if you are diabetic.
This could be a dry piece of toast and 125mL of clear juice or 2 rice crackers and 125 mL of clear juice.
No food or liquids are allowed within 2 hours before testing.
Other instructions remain the same.
What medications can affect the ENDOSURE test?
Opioid pain medications that slow the bowel: Codeine, Oxycodone, Hydrocodone +/- acetaminophen, Morphine, hydromorphone, Tramadol +/- acetaminophen
Medications that change intestinal movement: Metoclopramide, Domperidone, Itopride, Levosulpiride, Erythromycin, Dicyclomine, Hyoscine butylbromide, Loperamide
GLP-1 receptor agonists that slow stomach emptying: Tirzepatide – Mounjaro, Semaglutide – Ozempic/Wegovy
THC containing cannabis products
What medications are usually safe to continue before testing?
Acetaminophen, NSAIDs, Hormonal contraceptives, Endometriosis hormone therapy, Antidepressants, Neuropathic pain medication, Antiemetics
If in doubt please check with your doctor or pharmacist in advance of the test. Do not stop medications until speaking with your doctor or your pharmacist. Take your prescribed medications (other than ones listed as restricted) with small sips of water at least 2-hours before the test.
Should I stop my ADHD medications?
Do not stop taking any prescribed medications without your doctor’s approve, including for ADHD medications.
Can I continue using marijuana?
Preparations containing THC should be discontinued 30 days prior to ENDOSURE testing. Do not stop medications until speaking with your doctor or your pharmacist.
When do I see test results?
Results are usually uploaded to your patient file in the testing clinics EHR system. Patients generally book a separate consult with the attending clinician to review results. Check with your clinic to find out your next steps.
Can I rely on ENDOSURE test for a diagnosis?
ENDOSURE test is a highly accurate clinical tool providing supporting evidence and helps your clinician confidently diagnose endometriosis. Published results are as follows:
Females ≤35 years:
99% accurate
95% sensitivity
96% specificity
Females 36 years+:
98% accurate
91% sensitivity
95% specificity
Is the ENDOSURE test covered by provincial healthcare plans?
ENDOSURE test is only available at private clinics in Canada and is not covered by provincial plans (e.g. AHCIP, OHIP). Private insurance has reimbursed some patients, so receipts should be submitted. Talk to your clinician and ask for a referral, which may aid you when making a claim.
What are the most common endometriosis symptoms?
- Dysmenorrhea, Chronic pelvic pain (painful periods)
- Menorrhagia
- Dysuria, Dyschezia, or Dyspareunia (pain during urination, bowel movements or intercourse)
- IBS, GI issues
- Urinary infection unresponsive to treatment
- Unexplained fatigue or Brain fog
- Anxiety or depression
- Unexplained infertility
- Frequent miscarriage
- Previous high-risk pregnancy
What is endometriosis?
When endometrial-like tissue grows in areas other than the uterus, it’s known as endometriosis. Endometrial tissue lines the uterus, thickens each month in response to hormones, and if pregnancy is not achieve will shed during menstruation and leave the body. Endometrial lesions also build up in response to hormones, but the tissue has nowhere to go during menstruation. This results in pain & inflammation, and eventually scarring & adhesions.
Don’t see a clinic near you?
We’ll let you know when new clinics open.
Research
1. Noar, M.; Mathias, J.; Kolatkar, A. Gastrointestinal Myoelectrical Activity (GIMA) Biomarker for Noninvasive Diagnosis of Endometriosis. J. Clin. Med. 2024, 13,2866. https://doi.org/ 10.3390/jcm13102866
2. Noar M. AI-derived threshold score of intraabdominal myoelectrical activity predicts presence and stage of endometriosis with 100% accuracy. J Minim Invasive Gynecol. 2022 Nov;29(11):S4-S5.