Prostaglandin Fα (PGFα) plays a significant role in the pathophysiology of endometriosis particularly in relation to pain and gastrointestinal symptoms. PGFα causes “seizure-like activity” in the small intestine, causing increased smooth muscle contractions, altered gastrointestinal motility and the potential contribution to symptoms like abdominal pain and altered bowel habits. The EndoSure test captures the biometrics of gastrointestinal myoelectrical activity (GIMA) which has a distinct profile in the presence of endometriosis tissue (and raised PGF2α).